April 2025: Practical drug guides — ED combos, workout aids, and smarter medication swaps

What if one short article could save you hours of guessing about ED meds, workout supplements, or diabetes and nerve-pain options? In April 2025 we published four focused guides that cut through hype and give clear, usable information you can discuss with your clinician.

What we published

Low-dose sildenafil plus tadalafil-competitor approaches — This piece looks at people with stubborn erectile dysfunction who don’t respond to standard dosing. It explains why combining a low-dose sildenafil with a longer-acting agent or a tadalafil competitor can sometimes work better, outlines typical protocols reported in clinic case notes (including a small series with real-world outcomes from Perth), and lists practical safety checks: blood pressure monitoring, timing between doses, and drug-interaction red flags like nitrates or certain antifungals.

Androstenedione supplements — You’ll find a straight answer to whether this supplement helps workouts. Androstenedione is a hormone precursor that can raise testosterone in some users, but it carries risks: hormonal imbalance, possible liver stress, and banned-status in many sports. The article explains who might see meaningful gains, realistic timelines, and how to spot a legit product versus fakes or contaminants. It also gives simple lab tests you should consider if you try it.

Nine alternatives to Neurontin (2025) — If gabapentin (Neurontin) isn’t right for you, the roundup shows safer or more targeted choices this year. Short profiles cover topical lidocaine patches (Lidoderm, ZTlido), pregabalin, SNRIs like duloxetine, tricyclics for neuropathic pain, and non-drug options such as topical capsaicin or nerve blocks for certain cases. For each option we note typical benefits, common side effects, and situations where a switch makes sense.

Alternatives to pioglitazone — This guide compares pioglitazone with other diabetes tools, including pramlintide (Symlin), GLP-1 receptor agonists, SGLT2 inhibitors, metformin, and lifestyle strategies. It explains why someone might move off pioglitazone (weight gain, edema, other risks) and what trade-offs to expect when choosing an alternative.

Quick takeaways and what you can do now

If one of these topics hits home: keep notes for your next clinic visit. Bring symptoms, current meds, and any prior lab results. For ED combos, ask about cardiovascular checks and medication interactions. For supplements like androstenedione, ask for baseline hormonal and liver tests and verify product quality. For neuropathic pain and diabetes meds, discuss both symptom goals and long-term risks so you pick a plan that fits daily life.

April’s posts focus on real-world choices, safety checkpoints, and direct questions to raise with your provider — practical steps so you leave the consult with a clear plan, not more confusion.