Antioxidants: what they do and how to use them safely

Want a simple way to protect cells and slow damage from daily wear-and-tear? Antioxidants do that by neutralizing free radicals — unstable molecules that can harm DNA, proteins, and cell membranes. That sounds technical, but the takeaway is easy: eating antioxidant-rich foods supports overall health, and using supplements needs thought.

Top antioxidant foods

Real food is almost always the best source. Load your plate with colorful choices: berries (blueberries, strawberries), dark leafy greens (spinach, kale), red and orange vegetables (tomatoes, bell peppers, carrots), nuts (walnuts, almonds), and legumes. Don't forget green tea and coffee for flavonoids, and small amounts of dark chocolate (70% cocoa+) for polyphenols. Herbs and spices — turmeric, oregano, cinnamon — are tiny but powerful additions. Cooking can change antioxidant levels: quick steaming or raw in salads preserves vitamin C, while lightly sautéing tomatoes can increase lycopene absorption. Variety beats a single “superfood.”

Smart supplement use and safety tips

Supplements can help when diet falls short or when a doctor identifies a deficiency. Common antioxidant supplements include vitamin C, vitamin E, beta-carotene (a vitamin A precursor), selenium, and mixed polyphenol extracts. Typical context: vitamin C supplements often appear in 500–1,000 mg tablets while recommended daily intake is much lower; vitamin E daily needs are measured in milligrams (around 15 mg for adults). Avoid megadoses unless a clinician recommends them — high doses can cause harm. For example, high-dose beta-carotene increased lung cancer risk in heavy smokers in clinical trials, and very large vitamin E doses have been linked to higher bleeding risk.

Antioxidants can also interact with medicines. If you’re on blood thinners, cancer therapies, or immunosuppressants, check with your doctor before adding supplements. Some research shows high doses of vitamin C and E might blunt the muscular benefits of exercise training, so timing and dose matter if you train intensely.

Practical rules to follow: prioritize a varied diet rich in whole foods first; use supplements only to fill gaps or treat diagnosed deficiencies; pick products tested by third parties (USP, NSF); and tell your clinician about any supplements you take. If you smoke or have a chronic illness, get medical advice before starting antioxidant pills.

Want a quick day plan? Breakfast: berries and plain yogurt with walnuts. Lunch: mixed salad with spinach, tomatoes, and olive oil. Snack: green tea and an apple. Dinner: grilled salmon, steamed broccoli, and a turmeric-spiced side. Small, consistent choices like this add up more than a random high-dose pill.

Antioxidants are useful tools, not magic fixes. Focus on real food, be cautious with high-dose supplements, and check for drug interactions. That approach keeps benefits real and risks low.

/discover-the-antioxidant-powerhouse-superoxide-dismutase-supplements 25 February 2025

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