Obesity changes how drugs are absorbed, distributed, and cleared in the body. Standard doses often fail in obese patients, leading to treatment failure or toxicity. Learn how lean body weight, adjusted dosing, and therapeutic monitoring improve outcomes.
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Therapeutic drug monitoring helps ensure generic antiretrovirals with narrow therapeutic indexes work safely and effectively. It's not for all HIV drugs, but for key ones, it prevents toxicity and treatment failure when standard dosing fails.
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