ZTlido: What the Lidocaine Patch Does and When to Use It

Need localized relief from nerve pain? ZTlido is a prescription topical system that delivers lidocaine through the skin to numb a small area. Doctors usually prescribe it for postherpetic neuralgia (the lingering pain after shingles), but some clinicians may consider it for other localized neuropathic pain. It’s not a pill, so it targets nerves under the skin rather than treating the whole body.

How ZTlido works and what to expect

ZTlido contains 1.8% lidocaine in a thin patch designed to stick to intact skin. The patch releases lidocaine into the skin where it reduces nerve signals that cause pain. The result is localized numbness or dulling of pain in the treated area. Unlike some older patches labeled at 5% lidocaine, ZTlido’s delivery system aims to provide effective pain control with less adhesive bulk. Expect gradual pain relief after application; it may not be instant for everyone.

ZTlido is for short-term, targeted use. You should not use it on open wounds, infected skin, or areas with rash unless your doctor tells you to. Also avoid using it with other topical anesthetics at the same site to prevent too much lidocaine absorption.

How to apply ZTlido and safety tips

Wash and dry the application area. Do not shave irritated skin right before applying. Peel the patch from the backing and press it firmly onto the intact skin. Leave it on for up to 12 hours in any 24-hour period unless your prescriber instructs otherwise. After removal, fold the used patch in half with the sticky sides together and discard it safely—keep patches away from children and pets.

Do not cut ZTlido patches. Cutting can change how much drug is released and may lead to uneven dosing. Don’t expose the patch to external heat sources like heating pads, hot tubs, or prolonged sun exposure; heat can increase lidocaine absorption and raise the risk of side effects.

Common local side effects include redness, swelling, itching, or numbness at the application site. Systemic effects (like dizziness, ringing in the ears, or heart irregularities) are rare but possible if too much lidocaine is absorbed—stop use and contact a provider if you feel faint, confused, or have trouble breathing. Tell your doctor about other medications you take, especially antiarrhythmics or other local anesthetics, and mention liver problems since lidocaine is processed by the liver.

ZTlido requires a prescription. Buy it only from licensed pharmacies and avoid unverified online sellers. If cost is a concern, check manufacturer savings programs or talk to your pharmacist about alternatives. If your pain isn’t improving after a few applications or side effects are bothering you, contact your healthcare provider for a reassessment or different options.