How to manage an overdose of enalapril-hydrochlorothiazide 18 June 2023
Thomas Barrett 15 Comments

Understanding Enalapril-Hydrochlorothiazide Overdose

Before we dive into managing an overdose of enalapril-hydrochlorothiazide, it's important to understand what this medication is and how an overdose can occur. Enalapril-hydrochlorothiazide is a combination of two drugs used to treat high blood pressure (hypertension). Enalapril is an angiotensin-converting enzyme (ACE) inhibitor, while hydrochlorothiazide is a diuretic (water pill). Together, these drugs help lower blood pressure by relaxing blood vessels and removing excess fluid from the body.


An overdose can occur when someone takes more enalapril-hydrochlorothiazide than prescribed or recommended. Overdose symptoms may include dizziness, weakness, nausea, vomiting, and even more severe effects, such as low blood pressure, electrolyte imbalances, and kidney failure. If you or someone you know is experiencing an overdose, it's crucial to act quickly and follow the appropriate steps to manage the situation.

Recognizing the Signs of an Overdose

The first step in managing an enalapril-hydrochlorothiazide overdose is recognizing the signs and symptoms. Early detection can make a significant difference in the outcome of an overdose situation. Some common signs of an enalapril-hydrochlorothiazide overdose may include:


  • Dizziness or lightheadedness
  • Weakness or fatigue
  • Nausea and vomiting
  • Increased thirst or dry mouth
  • Confusion
  • Rapid or irregular heartbeat
  • Decreased urine output
  • Seizures or loss of consciousness

If you notice any of these symptoms in someone who has taken enalapril-hydrochlorothiazide, it's important to act fast and seek medical help immediately.

Calling for Emergency Help

If you suspect an enalapril-hydrochlorothiazide overdose, call your local emergency number or poison control center right away. Do not try to self-treat or wait for symptoms to improve. Prompt medical attention is crucial to minimize the risk of severe complications and improve the chances of a successful recovery.


When calling for help, provide as much information as possible about the situation, including the person's age, weight, and any existing medical conditions. Also, try to provide details about the medication, such as the dose taken, the time it was taken, and any other medications the person may be taking. This information will help the emergency responders provide the best possible care.

Administering First Aid

While waiting for medical help to arrive, there are some first aid measures you can take to assist the person experiencing an overdose. Keep in mind that these steps should not replace professional medical care, but they can help stabilize the person's condition until help arrives.


  • Keep the person calm and comfortable. Encourage them to lie down with their legs elevated slightly to help maintain blood flow to the brain.
  • Monitor the person's breathing and pulse. If they stop breathing or lose their pulse, begin CPR immediately.
  • Do not induce vomiting unless instructed to do so by a healthcare professional or poison control center. This could cause further harm to the person.
  • Stay with the person until medical help arrives. Your presence and support can be comforting during this challenging time.

Recovering from an Overdose

Once the person has received medical care for their enalapril-hydrochlorothiazide overdose, the recovery process will depend on the severity of the overdose and any complications that may have occurred. In some cases, the person may be able to return home after a short period of observation. In more severe cases, they may need to be hospitalized for further treatment and monitoring.


During recovery, it's essential for the person to follow their healthcare provider's instructions and attend any necessary follow-up appointments. They may also need to make adjustments to their medication regimen to prevent future overdoses. It's crucial to communicate openly with healthcare providers and ask questions about any concerns or uncertainties regarding the medication and its proper use.

Preventing Future Overdoses

Preventing future overdoses of enalapril-hydrochlorothiazide is vital to ensure the ongoing health and well-being of the person taking the medication. Some steps that can be taken to help prevent future overdoses include:


  • Take the medication exactly as prescribed and follow healthcare provider's instructions carefully.
  • Use a pill organizer or medication reminder app to help keep track of doses and avoid accidentally taking too much.
  • Keep all medications out of reach of children and pets to prevent accidental ingestion.
  • Discuss any concerns or questions about the medication with a healthcare provider. They can provide guidance and support to help ensure the safe and effective use of enalapril-hydrochlorothiazide.

By following these steps and staying vigilant about proper medication use, the risk of future enalapril-hydrochlorothiazide overdoses can be significantly reduced.

15 Comments

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    j jon

    June 19, 2023 AT 21:01
    Just took my pills and now I'm dizzy. Hope this isn't it.
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    Jules Tompkins

    June 20, 2023 AT 18:59
    Bro. I just saw a guy pass out in the pharmacy over this. Like, full-on dramatic collapse. The pharmacist had to call 911. I thought it was a movie scene.
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    Sabrina Bergas

    June 21, 2023 AT 16:30
    This article is so basic. If you're overdosing on ACE inhibitors with a diuretic, you're already in multi-organ failure territory. You don't need a blog post-you need a nephrologist, a cardiologist, and a damn ICU bed. Stop googling and start calling poison control.
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    Melvin Thoede

    June 22, 2023 AT 10:57
    This is actually super helpful. I've got my grandpa on this med and I was terrified something like this would happen. Thanks for laying it out so clearly. You're a lifesaver.
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    Suzanne Lucas

    June 23, 2023 AT 08:47
    I knew someone who did this on purpose. Like, full-on dramatic suicide attempt. They survived. But now they're on dialysis. And their cat ran away. The cat never forgave them.
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    Ash Damle

    June 23, 2023 AT 16:59
    I've been on this combo for 8 years and never had an issue. Just take it as directed. Don't be a dumbass. That's all you need to know
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    Kevin Ouellette

    June 24, 2023 AT 01:36
    If you're reading this and worried you might have taken too much-don't panic. Breathe. Call 911. Then call a friend. You're not alone. People get through this. You will too.
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    Tanya Willey

    June 24, 2023 AT 07:47
    This is all a lie. Big Pharma put this in the water to make you dependent. They want you to believe you need this pill. The real cure is sunlight and fasting. And no, I won't tell you where to buy the 'real' medicine. You'll find it when you're ready.
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    sarat babu

    June 24, 2023 AT 13:09
    I am from India, and here people take 5-6 tablets at once because they think it will work faster. I have seen 3 cases in my village. One died. One is in coma. One is fine. But the doctor said it was miracle. This is not a game. Please stop being stupid.
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    Richard H. Martin

    June 25, 2023 AT 04:13
    This is why we need border control for meds! Americans are too lazy to follow instructions. In my day, you took one pill and shut up. Now everyone's overdosing like it's a TikTok trend.
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    Tim H

    June 25, 2023 AT 05:35
    wait so if u take too much u get super tired and ur heart goes weird? i think i did that last week but i just slept it off lol
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    Umesh Sukhwani

    June 25, 2023 AT 14:37
    The clinical management of enalapril-hydrochlorothiazide overdose requires a multidisciplinary approach, including hemodynamic stabilization, electrolyte correction, and renal function monitoring. In severe cases, intravenous fluid resuscitation and vasopressor support may be necessary. Dialysis is rarely indicated but may be considered in refractory hypotension or acute renal failure.
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    Vishnupriya Srivastava

    June 26, 2023 AT 08:31
    The article is factually correct but lacks statistical context. Overdose incidence is 0.002% in controlled populations. Most cases are non-fatal with timely intervention. This post is fear-mongering by omission.
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    Armando Rodriguez

    June 26, 2023 AT 17:36
    Thank you for the detailed guidance. I appreciate the emphasis on calling emergency services immediately. As a healthcare provider, I've seen too many delays that cost lives. The first aid tips are accurate and practical. Please share this with anyone who might be managing chronic hypertension at home-it could save someone's life.
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    Matt Renner

    June 27, 2023 AT 13:22
    The clinical guidelines referenced in this article align with the 2023 ACC/AHA hypertension management update. It is critical to note that hydrochlorothiazide-induced hyponatremia and hypokalemia are the most common electrolyte derangements in overdose scenarios. Continuous cardiac monitoring and serial serum electrolyte assessments are mandatory. This summary is commendable for lay audiences.

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