Amitriptyline and nortriptyline are still used for depression and nerve pain, but they come with serious side effects like dry mouth, dizziness, heart risks, and cognitive issues. Learn how they work, who should avoid them, and how to use them safely.
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Ezetimibe and bempedoic acid are proven, non-statin options for lowering LDL cholesterol in people who can't tolerate statins. Both reduce heart risk, with ezetimibe being affordable and bempedoic acid offering proven cardiovascular benefits.
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Quality assurance units must operate independently from production to ensure product safety and regulatory compliance. Learn why separation is legally required, how failures lead to recalls, and what it takes to build a truly independent quality system.
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Mail-order pharmacies dispense 90% of all generic prescriptions in the U.S. with strict quality controls that often exceed retail standards. Learn how temperature tracking, packaging, and accreditation keep your meds safe-no matter how far they travel.
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Learn how to switch from a brand-name drug to an authorized generic - the same medicine at a lower price. Get practical tips on identifying, accessing, and switching safely with FDA-approved options.
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After the first generic enters the market, a cascade of competitors follows, triggering massive price drops. Learn how authorized generics, PBM contracts, and manufacturing bottlenecks shape the chaotic race to dominate generic drug markets.
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Learn how to use the FDA drug shortage database to check if your medication is in short supply, understand status codes, find alternatives, and report shortages. Essential for patients and caregivers.
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Learn how to search the FDA's FAERS database for side effect reports with practical tips on using the Public Dashboard, avoiding common misinterpretations, and understanding the limits of the data for real-world decisions.
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Generic drug shortages are caused by manufacturing failures, global supply chain concentration, and unprofitable pricing. Over 60% of shortages stem from production issues, with most active ingredients made in just two countries. Low margins drive manufacturers out, leaving no backup when things go wrong.
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Biosimilars offer real cost savings on expensive biologic drugs, with up to 85% discounts on list prices. Yet most spending still goes to originators due to rebate systems and slow adoption. Learn how much you could save and why competition isn’t moving faster.
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